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Determinação simultânea de precursores de serotonina - triptofano e 5-hidroxitriptofano - em café

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dc.contributor.author Martins, Ana Carolina C. L.
dc.contributor.author Silva, Tarliane M.
dc.contributor.author Gloria, M. Beatriz A.
dc.date.accessioned 2022-04-11T12:33:59Z
dc.date.available 2022-04-11T12:33:59Z
dc.date.issued 2010
dc.identifier.citation MARTINS, A. C. C. L.; SILVA, T. M.; GLORIA, M. B. A. Determinação simultânea de precursores de serotonina - triptofano e 5-hidroxitriptofano - em café. Química Nova, São Paulo, v. 33, n. 2, p. 316-320, 2010. pt_BR
dc.identifier.issn 1678-7064
dc.identifier.uri https://doi.org/10.1590/S0100-40422010000200016 pt_BR
dc.identifier.uri http://www.sbicafe.ufv.br/handle/123456789/13465
dc.description.abstract Epidemiological studies attributed positive effects in the central nervous system (CNS) to coffee. Among possible active constituents, serotonin, a neurotransmitter in the CNS, is present; but dietary sources do not cross the blood-brain barrier. Tryptophan and 5-hidroxytryptophan (5-HTP) are serotonin precursors and can affect brain concentrations. An ion-pair-HPLC, post-column derivatization with o-phthalaldehyde and fluorimetric detection before and after hydrolysis with NaOH and extraction with methanol: water was developed for the simultaneous determination of these compounds. It was selective, sensitive (LOD = 0.3 and 0.2 mg/mL), precise (91.3 and 94.2% recovery for tryptophan and 5-HTP, respectively), and linear from 0.3 to 40 mg/mL for both compounds. It was applied to green and roasted arabica and robusta coffees. pt_BR
dc.format pdf pt_BR
dc.language.iso pt_BR pt_BR
dc.publisher Sociedade Brasileira de Química pt_BR
dc.relation.ispartofseries Química Nova;v.33, n.2, 2010
dc.rights Open Access pt_BR
dc.subject Serotonin pt_BR
dc.subject Tryptophan pt_BR
dc.subject.classification Cafeicultura::Café e saúde pt_BR
dc.title Determinação simultânea de precursores de serotonina - triptofano e 5-hidroxitriptofano - em café pt_BR
dc.type Artigo pt_BR

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