dc.contributor.author |
Martins, Ana Carolina C. L. |
|
dc.contributor.author |
Silva, Tarliane M. |
|
dc.contributor.author |
Gloria, M. Beatriz A. |
|
dc.date.accessioned |
2022-04-11T12:33:59Z |
|
dc.date.available |
2022-04-11T12:33:59Z |
|
dc.date.issued |
2010 |
|
dc.identifier.citation |
MARTINS, A. C. C. L.; SILVA, T. M.; GLORIA, M. B. A. Determinação simultânea de precursores de serotonina - triptofano e 5-hidroxitriptofano - em café. Química Nova, São Paulo, v. 33, n. 2, p. 316-320, 2010. |
pt_BR |
dc.identifier.issn |
1678-7064 |
|
dc.identifier.uri |
https://doi.org/10.1590/S0100-40422010000200016 |
pt_BR |
dc.identifier.uri |
http://www.sbicafe.ufv.br/handle/123456789/13465 |
|
dc.description.abstract |
Epidemiological studies attributed positive effects in the central nervous system (CNS) to coffee. Among possible active constituents, serotonin, a neurotransmitter in the CNS, is present; but dietary sources do not cross the blood-brain barrier. Tryptophan and 5-hidroxytryptophan (5-HTP) are serotonin precursors and can affect brain concentrations. An ion-pair-HPLC, post-column derivatization with o-phthalaldehyde and fluorimetric detection before and after hydrolysis with NaOH and extraction with methanol: water was developed for the simultaneous determination of these compounds. It was selective, sensitive (LOD = 0.3 and 0.2 mg/mL), precise (91.3 and 94.2% recovery for tryptophan and 5-HTP, respectively), and linear from 0.3 to 40 mg/mL for both compounds. It was applied to green and roasted arabica and robusta coffees. |
pt_BR |
dc.format |
pdf |
pt_BR |
dc.language.iso |
pt_BR |
pt_BR |
dc.publisher |
Sociedade Brasileira de Química |
pt_BR |
dc.relation.ispartofseries |
Química Nova;v.33, n.2, 2010 |
|
dc.rights |
Open Access |
pt_BR |
dc.subject |
Serotonin |
pt_BR |
dc.subject |
Tryptophan |
pt_BR |
dc.subject.classification |
Cafeicultura::Café e saúde |
pt_BR |
dc.title |
Determinação simultânea de precursores de serotonina - triptofano e 5-hidroxitriptofano - em café |
pt_BR |
dc.type |
Artigo |
pt_BR |